Diclofenac plasma protein binding: PK-PD modelling in cardiac patients submitted to cardiopulmonary bypass

Diclofenac plasma protein binding: PK-PD modelling in cardiac patients submitted to cardiopulmonary bypass

Twenty-four surgical patients of both sexes without cardiac, hepatic, renal or endocrine dysfunctions were divided into two groups: 10 cardiac surgical patients submitted to myocardial revascularization and cardiopulmonary bypass (CPB), 3 females and 7 males aged 65 ± 11 years, 74 ± 16 kg body weigh...

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Bibliographic Details
Main Authors: J.O. Auler Jr., E.B. Espada, E. Crivelli, T.B.G. Quintavalle, A. Kurata, N.A.G. Stolf, A.M. Issy, O.E.D. Paschoa, M. Danhof, D.D. Breimer, D.A.F. Chamone, S.R.C.J. Santos
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1997-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
diclofenac
plasma protein binding
cardiopulmonary bypass
kinetic-dynamic parameters
analgesia
visual analogue scale
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300010

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