Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway

Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is the main cause for hepatocellular carcinoma (HCC). This study was intended to identify the function of long non-coding RNA (lncRNA) lncARSR in NAFLD and its role in human HCC cells (HepG2) proliferation and invasion. Methods LncARSR exp...

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Bibliographic Details
Main Authors: Yuan Chi, Zheng Gong, He Xin, Ziwen Wang, Zhaoyu Liu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Translational Medicine
Subjects:
Nonalcoholic fatty liver disease
Hepatocellular carcinoma
lncARSR
YAP1
IRS2
AKT
Online Access:http://link.springer.com/article/10.1186/s12967-020-02225-y

Internet

http://link.springer.com/article/10.1186/s12967-020-02225-y

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