CO2 Pneumoperitoneum Preserves β-Arrestin 2 Content and Reduces High Mobility Group Box-1 (HMGB-1) Expression in an Animal Model of Peritonitis

CO2 Pneumoperitoneum Preserves β-Arrestin 2 Content and Reduces High Mobility Group Box-1 (HMGB-1) Expression in an Animal Model of Peritonitis

Laparoscopy (LS) has been shown to decrease the inflammatory sequelae of endotoxemia. β-arrestin 2 plays an important function in signal transduction pathway of TLR4. High mobility group box-1 (HMGB-1) is involved in the delayed systemic inflammatory response. We investigated the effects of CO2 insu...

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Bibliographic Details
Main Authors: Angela Simona Montalto, Alessandra Bitto, Letteria Minutoli, Pietro Impellizzeri, Gaetano Costa, Natasha Irrera, Gabriele Pizzino, Francesco Squadrito, Domenica Altavilla, Carmelo Romeo
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/160568

Internet

http://dx.doi.org/10.1155/2015/160568

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