Cdk1 Coordinates Timely Activation of MKlp2 Kinesin with Relocation of the Chromosome Passenger Complex for Cytokinesis

Cdk1 Coordinates Timely Activation of MKlp2 Kinesin with Relocation of the Chromosome Passenger Complex for Cytokinesis

The chromosome passenger complex (CPC) must relocate from anaphase chromosomes to the cell equator for successful cytokinesis. Although this landmark event requires the mitotic kinesin MKlp2, the spatiotemporal mechanistic basis remains elusive. Here, we show that phosphoregulation of MKlp2 by the m...

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Bibliographic Details
Main Authors: Mayumi Kitagawa, Suet Yin Sarah Fung, Umar Farook Shahul Hameed, Hidemasa Goto, Masaki Inagaki, Sang Hyun Lee
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471400148X

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http://www.sciencedirect.com/science/article/pii/S221112471400148X

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