Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells

<p>Abstract</p> <p>Background</p> <p>Castration-resistance in prostate cancer (PC) is a critical event hallmarking a switch to a more aggressive phenotype. Neuroendocrine differentiation and upregulation of NFκB transcriptional activity are two mechanisms that have been...

Full description

Bibliographic Details
Main Authors: Apostolou Effie, Destouni Chariklia, Valeri Rosalia-Maria, Hatzidaki Eleana, Voutsadakis Ioannis A, Vlachostergios Panagiotis J, Patrikidou Anna, Daliani Danai, Papandreou Christos N
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/11/1/13