Endoplasmic reticulum stress, genome damage and cancer

Endoplasmic reticulum stress, genome damage and cancer

Endoplasmic reticulum (ER) stress has been linked to many diseases, including cancer. A large body of work has focused on the activation of the ER stress response in cancer cells to facilitate their survival and tumor growth, however, there are some studies suggesting that the ER stress response can...

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Bibliographic Details
Main Authors: Naomi eDicks, Karina eGutierrez, Marek eMichalak, Vilceu eBordignon, Luis B Agellon
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Oncology
Subjects:
Cell Death
DNA Breaks
Carcinogenesis
coping responses
Unfolded proteins
Chromatin damage
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00011/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00011/full

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