Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.

Bibliographic Details
Main Authors: Yifei Miao, Nassim E. Ajami, Tse-Shun Huang, Feng-Mao Lin, Chih-Hong Lou, Yun-Ting Wang, Shuai Li, Jian Kang, Hannah Munkacsi, Mano R. Maurya, Shakti Gupta, Shu Chien, Shankar Subramaniam, Zhen Chen
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02113-y