Effects of Differences in Lipid A Structure on TLR4 Pro-inflammatory Signaling and Inflammasome Activation
The vertebrate immune system exists in equilibrium with the microbial world. The innate immune system recognizes pathogen-associated molecular patterns via a family of Toll-like receptors that activate cells upon detection of potential pathogens. Because some microbes benefit their hosts, mobilizi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-06-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00154/full |