LTRs of Endogenous Retroviruses as a Source of Tbx6 Binding Sites

LTRs of Endogenous Retroviruses as a Source of Tbx6 Binding Sites

Retrotransposons are abundant in mammalian genomes and can modulate the gene expression of surrounding genes by disrupting endogenous binding sites for transcription factors (TFs) or providing novel TFs binding sites within retrotransposon sequences. Here, we show that a (C/T)CACACCT sequence motif...

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Bibliographic Details
Main Authors: Yukuto Yasuhiko, Yoko Hirabayashi, Ryuichi Ono
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Chemistry
Subjects:
endogenous retroviruses
retrotransposon
transcription factors
evolution
TBX6
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2017.00034/full

Internet

http://journal.frontiersin.org/article/10.3389/fchem.2017.00034/full

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