RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin

RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin

C. perfringens type F strains are a common cause of food poisoning and antibiotic-associated diarrhea. Type F strain virulence requires production of C. perfringens enterotoxin (CPE). In Caco-2 cells, high CPE concentrations cause necrosis while low enterotoxin concentrations induce apoptosis. The c...

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Bibliographic Details
Main Authors: Archana Shrestha, Iman Mehdizadeh Gohari, Bruce A. McClane
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
clostridium perfringens enterotoxin
apoptosis
necroptosis
rip1 kinase
rip3 kinase
mlkl
calpain
clostridium perfringens
rip1
rip3
enterotoxin
Online Access:https://doi.org/10.1128/mBio.02985-19

Internet

https://doi.org/10.1128/mBio.02985-19

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