Multivariate Analysis of Plasma Metabolites in Children with Autism Spectrum Disorder and Gastrointestinal Symptoms Before and After Microbiota Transfer Therapy

Multivariate Analysis of Plasma Metabolites in Children with Autism Spectrum Disorder and Gastrointestinal Symptoms Before and After Microbiota Transfer Therapy

Current diagnosis of autism spectrum disorder (ASD) is based on assessment of behavioral symptoms, although there is strong evidence that ASD affects multiple organ systems including the gastrointestinal (GI) tract. This study used Fisher discriminant analysis (FDA) to evaluate plasma metabolites fr...

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Bibliographic Details
Main Authors: James B. Adams, Troy Vargason, Dae-Wook Kang, Rosa Krajmalnik-Brown, Juergen Hahn
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Processes
Subjects:
autism spectrum disorder
gastrointestinal symptoms
biomarker
fisher discriminant analysis
multivariate statistics
leave-one-out cross-validation
plasma metabolites
fecal microbiota transplant
co-occurring conditions
Online Access:https://www.mdpi.com/2227-9717/7/11/806

Internet

https://www.mdpi.com/2227-9717/7/11/806

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