Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD.

Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD.

Genome-wide association studies identified single nucleotide polymorphisms (SNPs) in the nicotinic acetylcholine receptors (nAChRs) cluster as a risk factor for nicotine dependency and COPD. We investigated whether SNPs in the nAChR cluster are associated with smoking habits and lung function declin...

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Bibliographic Details
Main Authors: Simona E Budulac, Judith M Vonk, Dirkje S Postma, Mateusz Siedlinski, Wim Timens, Marike H Boezen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3305325?pdf=render

Internet

http://europepmc.org/articles/PMC3305325?pdf=render

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