Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD.
Genome-wide association studies identified single nucleotide polymorphisms (SNPs) in the nicotinic acetylcholine receptors (nAChRs) cluster as a risk factor for nicotine dependency and COPD. We investigated whether SNPs in the nAChR cluster are associated with smoking habits and lung function declin...
Main Authors: | Simona E Budulac, Judith M Vonk, Dirkje S Postma, Mateusz Siedlinski, Wim Timens, Marike H Boezen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3305325?pdf=render |
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