Genetic depletion studies inform receptor usage by virulent hantaviruses in human endothelial cells

Genetic depletion studies inform receptor usage by virulent hantaviruses in human endothelial cells

Hantaviruses are RNA viruses with known epidemic threat and potential for emergence. Several rodent-borne hantaviruses cause zoonoses accompanied by severe illness and death. However, assessments of zoonotic risk and the development of countermeasures are challenged by our limited knowledge of the m...

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Bibliographic Details
Main Authors: Maria Eugenia Dieterle, Carles Solà-Riera, Chunyan Ye, Samuel M Goodfellow, Eva Mittler, Ezgi Kasikci, Steven B Bradfute, Jonas Klingström, Rohit K Jangra, Kartik Chandran
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Hantavirus
receptor
Endothelial cells
CRISPR/Cas9
Online Access:https://elifesciences.org/articles/69708

Internet

https://elifesciences.org/articles/69708

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