The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders

The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders

Protein synthesis in eukaryotic cells is a complex, multi-step and tightly regulated process. Translation initiation, the rate limiting step in protein synthesis, is dependent on the activity of eukaryotic translation Initiation Factor 4E (eIF4E). eIF4E is the cap-binding protein which, in synergy w...

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Bibliographic Details
Main Authors: Inês S. Amorim, Gilliard Lach, Christos G. Gkogkas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
eIF4E
neurodevelopmental/neuropsychiatric disorders
anxiety
depression
protein synthesis
translation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00561/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00561/full

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