Inoculation site from a cutaneous melanoma patient treated with an allogeneic therapeutic vaccine: a case report

Inoculation site from a cutaneous melanoma patient treated with an allogeneic therapeutic vaccine: a case report

We have developed a therapeutic vaccine consisting of a mixture of lethally-irradiated allogeneic cutaneous melanoma cell lines with BCG and GM-CSF as adjuvants. The CSF-470 vaccine is currently being assayed in a Phase II-III trial against medium-dose IFN-a2b. All vaccinated patients immunized intr...

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Bibliographic Details
Main Authors: Mariana eAris, Alicia Inés Bravo, María Marcela Barrio, José eMordoh
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
cutaneous melanoma
Multiantigenic allogeneic therapeutic vaccine
Local injection reaction site
Vaccination site biopsy immune profiling
Local antigen presentation.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00144/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00144/full

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