Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Abstract Background Inflammatory breast cancer (IBC) is the most aggressive form of primary breast cancer. Using a custom-made breast cancer gene sequencing panel, we investigated somatic mutations in IBC to better understand the genomic differences compared with non-IBC and to consider new targeted...

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Bibliographic Details
Main Authors: Xu Liang, Sophie Vacher, Anais Boulai, Virginie Bernard, Sylvain Baulande, Mylene Bohec, Ivan Bièche, Florence Lerebours, Céline Callens
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Breast Cancer Research
Subjects:
Inflammatory breast cancer
Targeted NGS
Somatic mutation
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13058-018-1007-x

Internet

http://link.springer.com/article/10.1186/s13058-018-1007-x

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