The aging lung: tissue telomere shortening in health and disease

The aging lung: tissue telomere shortening in health and disease

Abstract Background Telomere shortening has been associated with several lung diseases. However, telomere length is generally measured in peripheral blood leucocytes rather than in lung tissue, where disease occurs. Consequently, telomere dynamics have not been established for the normal human lung...

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Bibliographic Details
Main Authors: Stephanie Everaerts, Elise J. Lammertyn, Dries S. Martens, Laurens J. De Sadeleer, Karen Maes, Aernoud A. van Batenburg, Roel Goldschmeding, Coline H. M. van Moorsel, Lieven J. Dupont, Wim A. Wuyts, Robin Vos, Ghislaine Gayan-Ramirez, Naftali Kaminski, James C. Hogg, Wim Janssens, Geert M. Verleden, Tim S. Nawrot, Stijn E. Verleden, John E. McDonough, Bart M. Vanaudenaerde
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Respiratory Research
Subjects:
Cystic fibrosis
Chronic obstructive pulmonary disease
Chronic hypersensitivity pneumonitis
Chronic lung allograft dysfunction
BOS
RAS
Online Access:http://link.springer.com/article/10.1186/s12931-018-0794-z

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http://link.springer.com/article/10.1186/s12931-018-0794-z

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