Insight Into the Role of Autophagy in Osteosarcoma and Its Therapeutic Implication

Osteosarcoma is an aggressive bone cancer that frequently metastasizes to the lungs. The cytotoxicity of most chemotherapeutics and targeted drugs in the treatment of osteosarcoma is partially lessened. Furthermore, there is a poor response to current chemo- and radiotherapy for both primary lesions...

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Bibliographic Details
Main Authors: Jianfang Niu, Taiqiang Yan, Wei Guo, Wei Wang, Zhiqing Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01232/full