Synthesis and Evaluation of Biological Activities of Bis(spiropyrazolone)cyclopropanes: A Potential Application against Leishmaniasis

Synthesis and Evaluation of Biological Activities of Bis(spiropyrazolone)cyclopropanes: A Potential Application against Leishmaniasis

This work focuses on the search and development of drugs that may become new alternatives to the commercial drugs currently available for treatment of leishmaniasis. We have designed and synthesized 12 derivatives of bis(spiropyrazolone)cyclopropanes. We then characterized their potential applicatio...

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Bibliographic Details
Main Authors: Olalla Barreiro-Costa, Gabriela Morales-Noboa, Patricio Rojas-Silva, Eliana Lara-Barba, Javier Santamaría-Aguirre, Natalia Bailón-Moscoso, Juan Carlos Romero-Benavides, Ana Herrera, Cristina Cueva, Lenin Ron-Garrido, Ana Poveda, Jorge Heredia-Moya
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
bis(spiropyrazolone)cyclopropanes
drugs
leishmaniasis cytotoxicity
ADME
Online Access:https://www.mdpi.com/1420-3049/26/16/4960

Internet

https://www.mdpi.com/1420-3049/26/16/4960

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