Population Pharmacokinetic Model of Iohexol in Dogs to Estimate Glomerular Filtration Rate and Optimize Sampling Time

Population Pharmacokinetic Model of Iohexol in Dogs to Estimate Glomerular Filtration Rate and Optimize Sampling Time

Monitoring iohexol plasma clearance is considered a useful, reliable, and sensitive tool to establish glomerular filtration rate (GFR) and early stages of kidney disease in both humans and veterinary medicine. The assessment of GFR based on iohexol plasma clearance needs repeated blood sampling over...

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Bibliographic Details
Main Authors: Sarah Baklouti, Didier Concordet, Vitaliano Borromeo, Paola Pocar, Paola Scarpa, Petra Cagnardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
dog
population pharmacokinetic
iohexol plasma clearance
sampling time optimization
glomerular filtration rate estimation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.634404/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.634404/full

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