Serotonin Transporter Genotype Modulates the Gut Microbiota Composition in Young Rats, an Effect Augmented by Early Life Stress

Serotonin Transporter Genotype Modulates the Gut Microbiota Composition in Young Rats, an Effect Augmented by Early Life Stress

The neurotransmitter serotonin (5-HT) plays a vital regulatory role in both the brain and gut. 5-HT is crucial for regulating mood in the brain as well as gastrointestinal motility and secretion peripherally. Alterations in 5-HT transmission have been linked to pathological symptoms in both intestin...

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Bibliographic Details
Main Authors: Sahar El Aidy, Anouschka S. Ramsteijn, Francisco Dini-Andreote, Roel van Eijk, Danielle J. Houwing, Joana F. Salles, Jocelien D. A. Olivier
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
serotonin transporter
intestinal bacteria
maternal separation
wild type
heterozygous
knockout rats
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00222/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00222/full

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