Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
Abstract Background The extent to which changes in gene expression can influence cardiovascular disease risk across different tissue types has not yet been systematically explored. We have developed an analysis pipeline that integrates tissue-specific gene expression, Mendelian randomization and mul...
Main Authors: | Kurt Taylor, George Davey Smith, Caroline L. Relton, Tom R. Gaunt, Tom G. Richardson |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-01-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13073-019-0613-2 |
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