Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells

Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells

Background: Treatment of metastatic melanoma possesses challenges due to drug resistance and metastases. Recent advances in targeted therapy and immunotherapy have shown clinical benefits in melanoma patients with increased survival. However, a subset of patients who initially respond to targeted th...

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Bibliographic Details
Main Authors: Rebaz Ahmed, Ranganayaki Muralidharan, Akhil Srivastava, Sarah E. Johnston, Yan D. Zhao, Suhendan Ekmekcioglu, Anupama Munshi, Rajagopal Ramesh
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
melanoma
HuR
MITF
metastases
siRNA
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/13/2/166

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https://www.mdpi.com/2072-6694/13/2/166

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