Anti-CXCR4 Antibody Combined With Activated and Expanded Natural Killer Cells for Sarcoma Immunotherapy

Anti-CXCR4 Antibody Combined With Activated and Expanded Natural Killer Cells for Sarcoma Immunotherapy

Sarcoma is one of the most severe forms of pediatric cancer and current therapies -chemotherapy and surgery- fail to eradicate the disease in half of patients. Preclinical studies combining new therapeutic approaches can be useful to design better therapies. On one hand, it is known that CXCR4 expre...

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Bibliographic Details
Main Authors: Maria Vela, David Bueno, Pablo González-Navarro, Ariadna Brito, Lucía Fernández, Adela Escudero, Jaime Valentín, Carmen Mestre-Durán, Marina Arranz-Álvarez, Rebeca Pérez de Diego, Marta Mendiola, José Juan Pozo-Kreilinger, Antonio Pérez-Martínez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
sarcoma
metastasis
chemokine C-X-C receptor 4 (CXCR4)
therapeutic antibody
activated and expanded natural killer (NKAE) cells
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01814/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01814/full

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