Population pharmacokinetics and exposure–response analyses of varenicline in adolescent smokers

Abstract Varenicline is an approved smoking cessation aid in adults. Population pharmacokinetics (popPK) and exposure–response (ER) (continuous abstinence rates [CAR] weeks 9‒12 and nausea/vomiting incidence) for varenicline in adolescent smokers were characterized using data from two phase 1 and on...

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Bibliographic Details
Main Authors: Daryl J. Fediuk, Kevin Sweeney, Vaishali Sahasrabudhe, Thomas McRae, Wonkyung Byon
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12645