Nanoparticle‐Mediated Intracellular Protection of Natural Killer Cells Avoids Cryoinjury and Retains Potent Antitumor Functions

Abstract The ability of natural killer (NK) cells to mediate potent antitumor immunity in clinical adoptive transfer settings relies, in large part, on their ability to retain cytotoxic function following cryopreservation. To avoid potential systemic toxicities associated with infusions of NK cells...

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Bibliographic Details
Main Authors: Xue Yao, Joshua J. Jovevski, Michaela F. Todd, Rui Xu, Yining Li, Jiao Wang, Sandro Matosevic
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.201902938