Seven perspectives on GPCR H/D-exchange proteomics methods [version 1; referees: 2 approved, 1 approved with reservations]

Recent research shows surging interest to visualize human G protein-coupled receptor (GPCR) dynamic structures using the bottom-up H/D-exchange (HDX) proteomics technology. This opinion article clarifies critical technical nuances and logical thinking behind the GPCR HDX proteomics method, to help s...

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Bibliographic Details
Main Author: Xi Zhang
Format: Article
Language:English
Published: F1000 Research Ltd 2017-01-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-89/v1