Postmortem analyses unveil the poor efficacy of decontamination, anti-inflammatory and immunosuppressive therapies in paraquat human intoxications.

BACKGROUND:Fatalities resulting from paraquat (PQ) self-poisonings represent a major burden of this herbicide. Specific therapeutic approaches have been followed to interrupt its toxic pathway, namely decontamination measures to prevent PQ absorption and to increase its excretion from organism, as w...

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Main Authors: Ricardo Jorge Dinis-Oliveira, Paula Guedes de Pinho, Liliana Santos, Helena Teixeira, Teresa Magalhães, Agostinho Santos, Maria de Lourdes Bastos, Fernando Remião, José Alberto Duarte, Félix Carvalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2745573?pdf=render