NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS

NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS

Natural killer (NK) cell activation is controlled by a balance of activating and inhibitory signals and cytokines such as IL-15. We previously identified cytokine-inducible SH2-containing protein (CIS) as a negative regulator of IL-15 signaling in NK cells under inflammatory conditions. While the fu...

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Bibliographic Details
Main Authors: Rebecca B. Delconte, Geoffrey Guittard, Wilford Goh, Soroor Hediyeh-Zadeh, Robert J. Hennessy, Jai Rautela, Melissa J. Davis, Fernando Souza-Fonseca-Guimaraes, Jacques A. Nunès, Nicholas D. Huntington
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
NK cell
CIS
priming
Homeostasis
IL-15
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00075/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00075/full

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