Metformin reduces androgen receptor and upregulates homeobox A10 expression in uterine endometrium in women with polycystic ovary syndrome

Metformin reduces androgen receptor and upregulates homeobox A10 expression in uterine endometrium in women with polycystic ovary syndrome

Abstract Background Polycystic ovary syndrome (PCOS) causes anovulation and is associated with a reduced clinical pregnancy rate. Metformin, which is widely used for treating PCOS, can lead to successful pregnancy by restoring the ovulation cycle and possibly improving endometrial abnormality during...

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Bibliographic Details
Main Authors: Miki Ohara, Hiromi Yoshida-Komiya, Miho Ono-Okutsu, Akiko Yamaguchi-Ito, Toshifumi Takahashi, Keiya Fujimori
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
Polycystic ovary syndrome
Metformin
Uterine endometrium
Androgen receptor
Homeobox A10
Online Access:https://doi.org/10.1186/s12958-021-00765-6

Internet

https://doi.org/10.1186/s12958-021-00765-6

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