The Morphology of Hydroxyapatite Nanoparticles Regulates Cargo Recognition in Clathrin-Mediated Endocytosis

The Morphology of Hydroxyapatite Nanoparticles Regulates Cargo Recognition in Clathrin-Mediated Endocytosis

The clathrin-associated protein adaptin-2 (AP2) is a distinctive member of the hetero-tetrameric clathrin adaptor complex family. It plays a crucial role in many intracellular vesicle transport pathways. The hydroxyapatite (HAp) nanoparticles can enter cells through clathrin-dependent endocytosis, i...

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Bibliographic Details
Main Authors: Cheng Zhu, Xuejie Zhou, Ziteng Liu, Hongwei Chen, Hongfeng Wu, Xiao Yang, Xiangdong Zhu, Jing Ma, Hao Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
nanoparticles
conformational change
endocytosis
cancer
molecular modeling and simulation
adaptin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.627015/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.627015/full

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