Corylin inhibits LPS-induced inflammatory response and attenuates the activation of NLRP3 inflammasome in microglia

Corylin inhibits LPS-induced inflammatory response and attenuates the activation of NLRP3 inflammasome in microglia

Abstract Background Inflammation has been found to be associated with many neurodegenerative diseases, including Parkinson’s and dementia. Attenuation of microglia-induced inflammation is a strategy that impedes the progression of neurodegenerative diseases. Methods We used lipopolysaccharide (LPS)...

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Bibliographic Details
Main Authors: Ming-Yii Huang, Chia-En Tu, Shu-Chi Wang, Yung-Li Hung, Chia-Cheng Su, Shih-Hua Fang, Chi-Shuo Chen, Po-Len Liu, Wei-Chung Cheng, Yu-Wei Huang, Chia-Yang Li
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Microglia
Corylin
MAPK signaling pathway
NLRP3 inflammasome
Anti-inflammation
Online Access:http://link.springer.com/article/10.1186/s12906-018-2287-5

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http://link.springer.com/article/10.1186/s12906-018-2287-5

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