Temporally Regulated Neural Crest Transcription Factors Distinguish Neuroectodermal Tumors of Varying Malignancy and Differentiation

Temporally Regulated Neural Crest Transcription Factors Distinguish Neuroectodermal Tumors of Varying Malignancy and Differentiation

Neuroectodermal tumor cells, like neural crest (NC) cells, are pluripotent, proliferative, and migratory. We tested the hypothesis that genetic programs essential to NC development are activated in neuroectodermal tumors. We examined the expression of transcription factors PAX3, PAX7, AP-2α, and SO...

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Bibliographic Details
Main Authors: Timothy R. Gershon, Orit Oppenheimer, Steven S. Chin, William L. Gerald
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Neural crest
neuroectodermal tumor
glia
melanocyte
development
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800788

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http://www.sciencedirect.com/science/article/pii/S1476558605800788

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