Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients

Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients

On-treatment platelet reactivity in clopidogrel-treated patients can be measured with several platelet function tests (PFTs). However, the agreement between different PFTs is only slight to moderate. Polymorphisms of the <i>CYP2C19</i> gene have an impact on the metabolization of clopido...

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Bibliographic Details
Main Authors: Renske H. Olie, Rachelle R. K. Hensgens, Petal A. H. M. Wijnen, Leo F. Veenstra, Bianca T. A. de Greef, Minka J. A. Vries, Paola E. J. van der Meijden, Jurriën M. ten Berg, Hugo ten Cate, Otto Bekers, Yvonne M. C. Henskens
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Clinical Medicine
Subjects:
pharmacogenetics
clopidogrel
platelet activation
platelet function test
<i>CYP2C19</i>
Online Access:https://www.mdpi.com/2077-0383/10/17/3992

Internet

https://www.mdpi.com/2077-0383/10/17/3992

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