Catechin and epicatechin reduce mitochondrial dysfunction and oxidative stress induced by amiodarone in human lung fibroblasts

Background: Amiodarone (AMD) and its metabolite N-desethylamiodarone can cause some adverse effects, which include pulmonary toxicity. Some studies suggest that mitochondrial dysfunction and oxidative stress may play a role in these adverse effects. Catechin and epicatechin are recognized as importa...

Full description

Bibliographic Details
Main Authors: Luciana Fernandes Silva Santos, Adriana Stolfo, Caroline Calloni, Mirian Salvador
Format: Article
Language:English
Published: Wiley 2017-06-01
Series:Journal of Arrhythmia
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427616301338