MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and/or apoptosis. MiR-221 and miR-222 were discovered to induce cell growth and cell cycle progression via direct targ...

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Bibliographic Details
Main Authors: Pei-yu Pu, Zhi-fan Jia, Guang-xiu Wang, Xiao Yue, Yan-chao Fu, An-ling Zhang, Lei Han, Chun-zhi Zhang, Qing-yu Zhang, Chun-sheng Kang
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/367