Dissolution and bioavailability improvement of bioactive apigenin using solid dispersions prepared by different techniques

Apigenin (APG) is a poorly soluble bioactive compound/nutraceutical which shows poor bioavailability upon oral administration. Hence, the objective of this research work was to develop APG solid dispersions (SDs) using different techniques with the expectation to obtain improvement in its in vitro d...

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Bibliographic Details
Main Authors: Sultan M. Alshehri, Faiyaz Shakeel, Mohamed A. Ibrahim, Ehab M. Elzayat, Mohammad Altamimi, Kazi Mohsin, Osaid T. Almeanazel, Musaed Alkholief, Abdullah Alshetaili, Bader Alsulays, Fars K. Alanazi, Ibrahim A. Alsarra
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S131901641830272X