Periodic fever syndromes: beyond the single gene paradigm

Periodic fever syndromes: beyond the single gene paradigm

Abstract Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease in Canada and is characterized by a clinical syndrome of episodic inflammatory symptoms. Traditionally, the disease is defined by autosomal recessive inheritance of MEFV gene variants, yet FMF also not...

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Bibliographic Details
Main Authors: Clara Westwell-Roper, Iwona Niemietz, Lori B. Tucker, Kelly L. Brown
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Hereditary autoinflammatory diseases
Familial Mediterranean fever
Biological therapy
Interleukin-1
Pyrin
Genetic association studies
Online Access:http://link.springer.com/article/10.1186/s12969-019-0324-7

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http://link.springer.com/article/10.1186/s12969-019-0324-7

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