Mechanism of Endoplasmic Reticulum Stress in Cerebral Ischemia

Mechanism of Endoplasmic Reticulum Stress in Cerebral Ischemia

Endoplasmic reticulum (ER) is the main organelle for protein synthesis, trafficking and maintaining intracellular Ca2+ homeostasis. The stress response of ER results from the disruption of ER homeostasis in neurological disorders. Among these disorders, cerebral ischemia is a prevalent reason of dea...

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Bibliographic Details
Main Authors: Yu Han, Mei Yuan, Yi-Sha Guo, Xin-Ya Shen, Zhen-Kun Gao, Xia Bi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebral ischemia
ER stress
unfolded protein response
apoptosis
inflammation
Ca2+ homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.704334/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.704334/full

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