The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice

The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice

CAR-like membrane protein (CLMP), an immunoglobulin cell adhesion molecule (IgCAM), has been implicated in congenital short-bowel syndrome in humans, a condition with high mortality for which there is currently no cure. We therefore studied the function of CLMP in a Clmp-deficient mouse model. Altho...

Full description

Bibliographic Details
Main Authors: Hanna Langhorst, René Jüttner, Dieter Groneberg, Azadeh Mohtashamdolatshahi, Laura Pelz, Bettina Purfürst, Kai M. Schmidt-Ott, Andreas Friebe, Fritz G. Rathjen
Format: Article
Language:English
Published: The Company of Biologists 2018-02-01
Series:Disease Models & Mechanisms
Subjects:
Cell adhesion
IgCAM
CLMP
Congenital short-bowel syndrome
Peristalsis
Hydronephrosis
Connexin43
Connexin45
Smooth muscle cells
Online Access:http://dmm.biologists.org/content/11/2/dmm032128

Internet

http://dmm.biologists.org/content/11/2/dmm032128

Similar Items