Clinical, Neuroimaging, and Pathological Analyses of 13 Chinese Leigh Syndrome Patients with Mitochondrial DNA Mutations

Clinical, Neuroimaging, and Pathological Analyses of 13 Chinese Leigh Syndrome Patients with Mitochondrial DNA Mutations

Background: Leigh syndrome (LS) is a rare disease caused by mitochondrial defects and has high phenotypic and genotypic heterogeneity. We analyzed the clinical symptoms, neuroimaging, muscular histopathology, and genotypes of 13 Chinese LS patients with mitochondrial DNA (mtDNA) mutations. Methods:...

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Bibliographic Details
Main Authors: Xiao-Lin Yu, Chuan-Zhu Yan, Kun-Qian Ji, Peng-Fei Lin, Xue-Bi Xu, Ting-Jun Dai, Wei Li, Yu-Ying Zhao
Format: Article
Language:English
Published: Wolters Kluwer 2018-01-01
Series:Chinese Medical Journal
Subjects:
Clinical Features; Leigh Syndrome; Mitochondrial DNA; Neuroimaging; Pathology
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=22;spage=2705;epage=2712;aulast=Yu

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http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=22;spage=2705;epage=2712;aulast=Yu

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