Modelling ischemia-reperfusion injury (IRI) in vitro using metabolically matured induced pluripotent stem cell-derived cardiomyocytes

Modelling ischemia-reperfusion injury (IRI) in vitro using metabolically matured induced pluripotent stem cell-derived cardiomyocytes

Coronary intervention following ST-segment elevation myocardial infarction (STEMI) is the treatment of choice for reducing cardiomyocyte death but paradoxically leads to reperfusion injury. Pharmacological post-conditioning is an attractive approach to minimize Ischemia-Reperfusion Injury (IRI), but...

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Bibliographic Details
Main Authors: Alejandro Hidalgo, Nick Glass, Dmitry Ovchinnikov, Seung-Kwon Yang, Xinli Zhang, Stuart Mazzone, Chen Chen, Ernst Wolvetang, Justin Cooper-White
Format: Article
Language:English
Published: AIP Publishing LLC 2018-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5000746

Internet

http://dx.doi.org/10.1063/1.5000746

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