Prolonged mechanical ventilation worsens sepsis-induced diaphragmatic dysfunction in the rat.

BACKGROUND:Short-term mechanical ventilation (MV) protects against sepsis-induced diaphragmatic dysfunction. Prolonged MV induces diaphragmatic dysfunction in non-septic animals, but few reports describe the effects of prolonged MV in sepsis. We hypothesized that prolonged MV is not protective but w...

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Bibliographic Details
Main Authors: Matthieu Le Dinh, Serge Carreira, Julie Obert, Ghislaine Gayan-Ramirez, Bruno Riou, Maud Beuvin, Thomas Similowski, Catherine Coirault, Alexandre Demoule
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6070213?pdf=render