Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial.

Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial.

Vaccination against complex pathogens such as typhoidal and non-typhoidal Salmonella requires the concerted action of different immune effector mechanisms. Outer membrane proteins (Omps) of Salmonella Typhi are potent immunogens, which elicit long-lasting and protective immunity. Here, we followed t...

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Bibliographic Details
Main Authors: Juan Manuel Carreño, Christian Perez-Shibayama, Cristina Gil-Cruz, Constantino Lopez-Macias, Pietro Vernazza, Burkhard Ludewig, Werner C Albrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5453566?pdf=render

Internet

http://europepmc.org/articles/PMC5453566?pdf=render

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