Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells

Abstract Extracellular vesicles (EVs) are well-known mediators in intercellular communication playing pivotal roles in promoting liver inflammation and fibrosis, events associated to hepatic lipotoxicity caused by saturated free fatty acid overloading. However, despite the importance of lipids in EV...

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Bibliographic Details
Main Authors: Sandra Buratta, Y. Shimanaka, E. Costanzi, S. Ni, L. Urbanelli, N. Kono, F. Morena, K. Sagini, S. Giovagnoli, R. Romani, M. Gargaro, H. Arai, C. Emiliani
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84268-9