Comparison of the Effects of Na+ and K+ Channel Blockers on the Electrophysiological Properties of the Pulmonary Veins in Patients with Atrial Fibrillation

Comparison of the Effects of Na+ and K+ Channel Blockers on the Electrophysiological Properties of the Pulmonary Veins in Patients with Atrial Fibrillation

Introduction: We assessed the effects of pilsicainide, a pure Na+ channel blocker, and nifekalant, a pure rapid delayed rectifier potassium current (IKr) blocker, on the electrophysiological characteristics within the pulmonary vein (PV) and at the PV-left atrial (LA) junction. Methods and Results:...

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Bibliographic Details
Main Authors: Tomoo Yasuda, MD, Koichiro Kumagai, MD, Masahiro Ogawa, MD, Hideko Nakashima, MD, Bo Zhang, PhD, Shin-ichiro Miura, MD, Keijiro Saku, MD
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Arrhythmia
Subjects:
Nifekalant
Pulmonary vein
Atrial fibrillation
Pilsicainide
Electrophysiology
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427610800250

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http://www.sciencedirect.com/science/article/pii/S1880427610800250

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