NKAP alters tumor immune microenvironment and promotes glioma growth via Notch1 signaling

Abstract Background Glioma is one of the most aggressive malignant brain tumors which is characterized with highly infiltrative growth and poor prognosis. NKAP (NF-κB activating protein) is a widely expressed 415-amino acid nuclear protein that is overexpressed by gliomas, but its function in glioma...

Full description

Bibliographic Details
Main Authors: Guangyan Gu, Taihong Gao, Lu Zhang, Xiuyang Chen, Qi Pang, Yanan Wang, Dan Wang, Jie Li, Qian Liu
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TAM
Online Access:http://link.springer.com/article/10.1186/s13046-019-1281-1