Two different interictal spike patterns anticipate ictal activity in vitro

Two different interictal spike patterns anticipate ictal activity in vitro

4-Aminopyridine (4AP, 50 μM) induces interictal- and ictal-like discharges in brain slices including parahippocampal areas such as the entorhinal cortex (EC) but the relation between these two types of epileptiform activity remains undifined. Here, by employing field potential recordings in rat EC s...

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Bibliographic Details
Main Authors: Massimo Avoli, Gabriella Panuccio, Rochelle Herrington, Margherita D'Antuono, Philip de Guzman, Maxime Lévesque
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Neurobiology of Disease
Subjects:
4-Aminopyridine
CA3 subfield
Entorhinal cortex
High frequency oscillations
Ictogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112003877

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http://www.sciencedirect.com/science/article/pii/S0969996112003877

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