DNA methylation of the Rtl1 promoter in the placentas with fetal growth restriction

Background: Small for gestational age (SGA) babies experience fetal growth restriction because of placental insufficiency, and aberrant fetal growth has been linked to DNA methylation in the placenta. An imprinted gene encoding retrotransposon-like protein 1 (RTL1) is regulated by DNA methylation in...

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Bibliographic Details
Main Authors: Kazumichi Fujioka, Kosuke Nishida, Mariko Ashina, Shinya Abe, Sachiyo Fukushima, Toshihiko Ikuta, Shohei Ohyama, Ichiro Morioka, Kazumoto Iijima
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Pediatrics and Neonatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957218305503